Vitamin D & Analogues

FORMULATING THE FUTURE FOR BETTER HEALTH

Functioning as the global outsourcing partner for other pharmaceutical companies; aiding them in development and scale-up production via its high potency supply of compounds; Dishman first realized the need of the hour with Vitamin D because of its elaborate research on its therapeutic uses that covers wide range of medical conditions.

EVOLUTION TOWARDS THE VITAMIN D VALUE CHAIN

Crucial for every life stage, Vitamin D forms the essence of human health. Hence, keeping wellness as our primary objective, we acquired Solvay Pharmaceuticals’ Veenendaal, Netherlands plant, only to re-associate with its core in 2006, as Dishman CARBOGEN AMCIS. This specially focused on manufacturing cholesterol, serving as a precursor to vitamin D & its analogues.

As a multifaceted organization with a high degree groundwork, we established greener processes to be manufactured in a budgeted environment. Hence, we ensure the extraction of this cholesterol from sheep wool, making it a vegan source required to form a strong base for the formulations.

Gradually, with a steadfast strategy, entrepreneurial spirit and a rising demand for the application of this raw material in various sectors: as a natural course towards the extension of existing and acquired business, we forayed into developing a wide spectrum of products for the pharmaceutical, nutraceutical and holistic animal nutrition verticals of Vitamin D3. This derivative if taken in the right quantity, can cure to the roots of many diseases, resulting in complete wellbeing.

VITAMIN D - THE RIGHT STEP TO WELL-BEING

In the pursuit of developing a world-wide circuit in the supply of Vitamins and its analogues, Dishman has initiated with the establishment of US-FDA and WHO-cGMP compliant fully-integrated manufacturing unit, at Bavla, based in Gujarat, India, which is also ISO 9001:2015 certified.

Its core lies in its CRAMs model capabilities that umbrellas an entire gamut of services from production of raw materials to developing the final products as well as market the same under customer’s private label. This lead us running in the forefront with the capacity to manufacture 1000 MT annually and simultaneously catering to specifically engineered requirements of our clients, all at one place.

Vitamin D & its Analogues PERMISSIBLE TO USE IN:
Sr No. Vitamin D Analogue Type Importance Humans Animals
1 Cholecalciferol (D3) The analogues for Vitamin D3 find strong demands in Pharmaceutical and Veterinary industry.
Its varied applications focus on prevention and treatment of not only osteoporosis or decalcification of bones, but also other bone growth disorders such as rickets, osteomalacia and specific liver and parathyroid glands abnormalities.
The substance’s presence in the body of humans and/or animals is especially useful against secondary hyperparathyroidism.
associated with chronic kidney disease (CKD).
2 Calcifideol (25 OH D3)
3 Calcitriol (1,25 OH D3)
4 Alfacalcidol
5 Ergocalciferol (D2)

Hence, with our new venture under this unit, we are seeking the path to advance towards creating a revolution and generate highly potent products under Pharma APIs, Nutraceuticals, Vitamin D Formulations and complete animal nutrition products.

Pharmaceutical
APIs
Vitamin D Formulations & CRAMS Services Animal Nutrition: Feed
Products & Vitamin Premixes

 

WHAT IS VIT D ALL ABOUT?

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Chemically, this Vitamin refers to a group of fat-soluble secosteroids, needed for calcium absorption from the intestinal tract, and for the regulation of blood phosphorus levels, which are essential to grow and maintain strong and healthy bones.

Indeed, Vitamin D play a vital role in brain development, muscle function, maintaining a healthy respiratory and immune system, optimal cardiac function. It also strengthens our bodies to resist illnesses such as diabetes, asthma, chronic pains, cancer, infections, multiple sclerosis, psoriasis, depression and much more.

However, if there is a Vitamin D deficiency, then it leads to bone disorders such as rickets, osteomalacia and osteoporosis in adults as well as children, alike. Therefore, its presence is a ray of hope to live with an elevated sense of well-being and that is why it is also known as the ‘sunshine vitamin’.

CHEMICAL BREAKDOWN OF VIT D IN THE BODY

Vitamin D, which is ideally present in inactive form in the human body, gets activated in the presence of sunlight to process the release of Calcifediol. This Calcifediol is then metabolized in the kidney to release Calcitriol which is further absorbed by the intestine, kidney and bones. Following this, the bones mobilize the secretion of Calcium and Phosphate in the parathyroid gland to maintain the optimum balance of these elements, prerequisite for strong bones.

Vitamin D
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